Wall Street was lower on Monday as a slide in Apple shares due to demand worries hit the technology sector, while conflicting signals of a potential truce in the China-US trade dispute added to market jitters.
Shares of Apple Inc fell 2.5 percent after the Wall Street Journal reported the company has cut production orders in recent weeks for all three iPhone models launched in September.
The iPhone maker's stock is down 11.6 percent this month following the company's lower-than-expected sales forecast for the holiday quarter and a string of weak forecasts from several of its suppliers.
Shares of Apple suppliers were also hit, with Lumentum Holdings Inc, Universal Display Corp, Cirrus Logic Inc and Skyworks Solutions Inc down between 1.5 percent and 4.8 percent.
The rest of the so-called FAANG stocks - Facebook Inc, Amazon.com Inc, Netflix Inc and Alphabet Inc - shed between 3 percent and 1.3 percent.
Micron Technology Inc fell 1.7 percent after a report that Chinese authorities have alleged "massive evidence" of antitrust violations by the world's top three memory chip makers - the latest industrial spat that threatens to upset global trade relations.
The Philadelphia SE Semiconductor index dropped 1.1 percent, extending losses from the previous session after an underwhelming forecast from Nvidia Corp weighed on the sector.
Eight of the 11 major S&P sectors were lower, led by a 1.9 percent decline in technology shares.
At 9:52 a.m. ET, the Dow Jones Industrial Average was down 96.70 points, or 0.38 percent, at 25,316.52, the S&P 500 was down 11.02 points, or 0.40 percent, at 2,725.25 and the Nasdaq Composite was down 72.18 points, or 1.00 percent, at 7,175.69.
Over the weekend, Asia-Pacific leaders failed to agree on a communique for the first time ever at a meeting in Papua New Guinea with US-China trade worries on the forefront.
US Vice President Mike Pence said on Saturday the United States will not back down from its trade dispute with China, and might even double its tariffs, unless Beijing bows to US demands, dampening Friday's trade optimism that was fueled by US President Donald Trump's comments.
"Markets are a little bit cautious with regard to the comments that Pence made over the weekend and the fact that they couldn't get a communique out of APEC meeting," said Robert Pavlik, chief investment strategist and senior portfolio manager at SlateStone Wealth LLC in New York.
Boeing Co and Caterpillar Inc, seen as trade sensitive stocks, fell 1.5 percent and 1 percent, respectively.
China's JD.com Inc slipped 6.2 percent after reporting third-quarter revenue below analysts' estimates on sluggish sales in its core e-commerce business.
Declining issues outnumbered advancers for a 1.30-to-1 ratio on the NYSE and for a 1.58-to-1 ratio on the Nasdaq.The S&P index recorded 22 new 52-week highs and three new lows, while the Nasdaq recorded 11 new highs and 39 new lows